Mutation: In spike protein of SARS-CoV-2 Variant
نویسندگان
چکیده
منابع مشابه
Antimyogenic Effect of SARS-CoV Spike Protein in C2C12 Myoblasts
C2C12 myoblasts serve as well-established model system to study myogenesis, as they fuse to form multinucleated myotubes. Severe acute respiratory syndrome coronavirus (SARS–CoV) spike (S) protein plays a crucial role in viral entry. Exogenous expression of S protein in C2C12 myoblasts inhibits the formation of myotubes. Global changes in gene expression were studied in C2C12 cells expressing S...
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We have previously shown that the nucleocapsid protein of SARS-associated coronavirus (SARS-CoV) activated cyclooxygenase-2 (COX-2) expression. In this study, we identified another viral protein, the spike of SARS-CoV, which played an important role in virus-stimulated COX-2 expression after screening all genes from the SARS-CoV genome. We found that an upstream calcium-dependent PKC isozyme PK...
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ژورنال
عنوان ژورنال: Acta Scientific Microbiology
سال: 2021
ISSN: 2581-3226
DOI: 10.31080/asmi.2020.04.0767